Progresses on the effects and mechanisms of stress on gut microbiota / 生理学报

Stress is the non-specific systemic response that occurs when the body is stimulated by various factors, and it can affect multiple systems of the body. Recent studies have shown that gut microbiota is an essential part of human microecology, and plays a pivotal role in keeping the body healthy. Stress can result in gut dysbiosis by affecting the function of intestinal mucosal barrier, intestinal immune and gastrointestinal motility. This article reviewed the alteration of gut microbiota caused by stress and the possible mechanisms involved.

Strategy and novel technology for treatment of Ebola virus disease: Research advances / 国际药学研究杂志

Ebola virus is a highly virulent pathogen causing severe hemorrhagic fever with a high fatality rate in humans. Although safe and effective therapeutics and treatment strategies or other medicinal agents in post-exposure therapeutics for the prevention of Ebola hemorrhagic are currently unavailable, a significant effort has been put forth to identify several promising candidates for post-exposure therapeutics and treatment of Ebola hemorrhagic fever. These potential strategies and novel technology include monoclonal antibody cocktail, polymerase inhibitors and lipid nanoparticle/small interfering RNA. This article summarizes recent advances in therapeutics and treatment strategies and novel technology in Ebola virus post-infection in small animals and non-human primates.